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Extension > Agriculture > Livestock > Swine Extension > Swine feed medications transitioning from over-the-counter (OTC) to veterinary feed directive (VFD) status

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Swine feed medications transitioning from over-the-counter (OTC) to veterinary feed directive (VFD) status

Sarah Schieck

On January 1, 2017, the U.S Food and Drug Administration's (FDA) new regulation addressing on-farm antibiotic use in food-animal production will take effect. The purpose of this publication is to identify which swine medications will be affected by these changes. FDA's effort is aimed to eliminate the use of medically important (to human illness) antibiotics for growth promotion purposes in food-animal production and to bring therapeutic use of antibiotics in feed and water - to treat, control, or prevent specific disease - under additional veterinary oversight. The new requirements will affect producers, veterinarians, feed mills and suppliers.

Swine medications transitioning from OTC to VFD

Starting January 1, 2017, all feed uses of the following medications approved for swine use, alone and in combination with other medications, will require a VFD.

Established drug name Examples of trade name(s)$
Chlortetracycline (CTC) Aureomycin®, Chlorachel™, Chloratet, ChlorMax™, CLTC, CTC®, Deracin®, Pennchlor®, Pfichlor™
Chlortetracycline/sulfamethazine Aureomix® S
Chlortetracycline /sulfamethazine /penicillin* Chlorachel™/Pfichlor SP, ChlorMax™ SP, Pennchlor SP
Hygromycin B Hygromix
Lincomycin Lincomix®
Oxytetracycline (OTC) OXTC®, Oxytetracycline, Pennox™, Terramycin®
Oxytetracycline /neomycin* Neo-Oxy®, Neo-Terramycin®
Penicillin+ Penicillin G Procaine
Tylosin Tylan®, Tylosin®, Tylovet®
Tylosin/sulfamethazine* Tylosin Plus Sulfamethazine, Tylan® Sulfa-G
Virginiamycin Stafac®, Virginiamycin

Note: apramycin, erythromycin, neomycin (alone), oleandomycin+, sulfamerazine, and sulfaquinoxaline are also approved for use in feed and are expected to transition to VFD status, but are not marketed at this time. If they return to the market after January 1, 2017, they will require a VFD.

$Type A medicated articles used to manufacture medicated feeds, all products may not be marketed at this time.
*Fixed-ratio, combination drug +Currently only approved for production uses

Current swine VFD medications that will remain VFD medications

Medications not affected by FDA's antibiotic changes

Antimicrobials that are not medically important

Other medications (that are not antimicrobials)

What does "medically important" mean?

An antibiotic is considered medically important if it is used, or antibiotics in the same family of medications, is used in human or animal medicine.

FDA's new antibiotic regulations defined

Note:This information was adapted from a FDA fact sheet and was up-to-date as of August 2016. As the industry transitions, Center for Veterinary Medicine anticipates additional changes during the coming months to this information. Please check for the most recent updates.

References and additional resources


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